Notes on Corynebacterium

Rahul's Noteblog Notes on Bacteriology Notes on Corynebacterium

Genus: Corynebacterium.

• Gram +; non-spore forming, immotile, aerobi Corynebacterium.

• Widespread in nature.

• Forms metachromatic granules.

• Generally inhabit the soil and are found on the surface of plants.

• Gram-positive pleomorphic rods that are often club-shaped and arranged to form V shapes or palisades.

• Facultative anaerobes, but some are strict aerobes.

• Form volutin granules and are dyed with methylene blue.

• Usually thrive in the throat, but the Corynebacterium diphtheria can cause disease.

• Non-motile, non-spore-forming.

Corynebacterium diphtheriae:

• Gray or black colonies growing on tellurite medium.

• Granules produced on Loeffler's medium.

• Toxin genes (lysogeny, beta-corynephage) spread one bacterium to another.

• Spreads by respiratory droplets.

Pathogenesis:

• Not invasive.

• Colonizes epithelium of oropharynx or skin.

• Diphtheria toxin ribosylates EF-2, and inhibits protein synthesis.

• Grey pseudomembrane obstructs larynx/trachea.

• May cause heart/nerve damage.

Diseases:

• Diphtheria: pseudomembrane, bull neck, myocarditis, recurrent laryngeal n. palsy.

Lab tests:

• Elek test +.

Treatment:

• Erythromycin and antitoxin.

Vaccinations:

• DTap, DTP or Td.

Additional Readings:

Basic Bacteriology

1. Bacterial Locations and Toxins
2. Growth Medias and Oxygen Requirements
3. Staphylococus
4. Streptococcus
5. Enterococcus
6. Bacillus
7. Listeria
8. Corynebacterium
9. Actinomyces
10. Nocadria
11. Mycobacterium
12. Clostridium
13. Neisseria
14. Pseudomonas
15. Legionella
16. Bordetella
17. Francisella
18. Brucella
19. Campylobacter
20. Escherichia
21. Shigella
22. Klebsiella
23. Salmonella
24. Yersinia
25. Proteus
26. Vibrio
27. Pasteurella
28. Haemophilus
29. Bacteriodes and Prevotella
30. Treponema
31. Borrelia
32. Rickettsia
33. Coxiella
34. Ehrlichia
35. Chlamydia
36. Mycoplasma
37. What is an ELEK's Test?
38. Causes of Orchitis
39. What is Leprosy?
40. What is Folliculitis?
41. What is Botulism?
42. How to interpret PPD (Purified Protein Derivative) results?
43. Prenatal Infections

Medical Images

Useful Medical Images & Diagrams (link opens in a new window)

Random Pages:

One Powerful Prayer written by an Anonymous Author	Review of eBoundhost VPS hosting
Video of me playing Hagood Hardy`s "The Homecoming"	Notes on Female Reproductive System
Notes on Osteology of Pectoral Region	Notes on Chlamydia
Notes on Glycogen, Gluconeogenesis, and Hexose Monophosphate Shunt	Causes and Complications of Arteriovenous Fistulas
FAQ on Male Reproduction	Notes on Jaundice
Notes on Basic Gastrointestinal Physiology	Life in a Drop of Water
My First Computer - Pentium with Windows 95	What is an ELEK`s Test?
Why did I decide to become a doctor? Medical School Admissions Essay	Video: Titanic Piano Theme: The Portrait
Corporate Failure: The Enron Case	My Experience during the Iraqi Invasion of Kuwait
USMLE Blood Lab Values	Regulation of Heart Rate by Autonomic Nervous System
Images of Antibodies	Signs you`re being married to for Green Card
Notes on Female Reproductive System	Differentiation and Anatomy of a Blastocyst
Notes on Cell Components	Notes on Nervous Tissue
Voices from Hell: My Experience in Mussoorie, India	Video of Cardiology Examination in a Clinical Setting

Please Do Not Reproduce This Page

This page is written by Rahul Gladwin. Please do not duplicate the contents of this page in whole or part, in any form, without prior written permission.